Biphasic Response of Action Potential Duration to Sudden Sympathetic Stimulation in Anesthetized Cats
نویسندگان
چکیده
منابع مشابه
Biphasic response of action potential duration to sudden sympathetic stimulation in anesthetized cats.
Although certain roles of the sympathetic nervous system have been suggested as possible mechanisms of life-threatening arrhythmias and sudden cardiac death, the dynamic electrophysiological response to sympathetic activation remains unclear. The aim of this study was to investigate the dynamic response of action potential duration (APD) to sudden sympathetic stimulation (SYM) using monophasic ...
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INTRODUCTION i.v. haloperidol is used commonly for sedation in critically ill patients. However, i.v. haloperidol has been shown to cause the life-threatening ventricular tachyarrhythmia torsades de pointes. Mechanisms by which haloperidol causes torsades de pointes have not been widely investigated in controlled studies. STUDY OBJECTIVES To determine the effects of i.v. haloperidol on electr...
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I(Ks), the slowly activating component of the delayed rectifier current, plays a major role in repolarization of the cardiac action potential (AP). Genetic mutations in the alpha- (KCNQ1) and beta- (KCNE1) subunits of I(Ks) underlie Long QT Syndrome type 1 and 5 (LQT-1 and LQT-5), respectively, and predispose carriers to the development of polymorphic ventricular arrhythmias and sudden cardiac ...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2003
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.67.876